How to play Murder Hobo Tavern Brawl!

About Murder Hobo Tavern Brawl!, from BoardGameGeek:

In this chaotic fantasy themed battle card brawl, players use 42 hero cards and 46 weapon and spell cards to build their defence and attack against multiple opponents. Take it in turns to use hero cards to act as shields, launch weapons, or use special abilities. Stack Attack Cards into combos to deal increasing damage. Build your attacks, but don't neglect your defence! Attack your opponent's defence pile until they have no cards left, then attack then while they're vulnerable to send them out of the game. Watch out for special abilities that might ruin your strategy and turn the tables! The last player standing is the victor of Murder Hobo Tavern Brawl. -description from the designer