About 50 Clues: Down in the Depths, from BoardGameGeek:
Down in the Depths is the second episode of the story-driven escape game trilogy, Sunshine Island. 50 Clues is an award-winning immersive puzzle game that offers the experience of an escape room, but in a format that can be played at home. You combine objects, solve puzzles and decipher codes to complete the story. A smartphone or tablet keeps track of the solutions and provides multistep hints if the need arises.
The situation has deteriorated from critical to almost impossible. An infectious and deadly fungus has spread on the island of Bornholm. A biological warfare agent that's out of control. Will you find the results of your sister's research located in the underground complex in time? If you succeed, then you can prevent a global catastrophe from happening, but a mysterious pharmaceutical company has other plans. Take on a difficult mission in the role of Sigrid and solve the mystery.
Players work through a numbered deck of cards, solving puzzles trying to solve the mystery.
-description from the publisher
