The Hand of Destiny

From BoardGameGeek:

Waves of minions accompany an evil monster ravaging the land in the Realm of Shadows. Fight off each wave and defeat the menacing final boss to bring light to the darkness! The Hand of Destiny is a no-table-needed, solo game played completely in your hands. You'll use your hero's limited strength resources and unique abilities to vanquish foes and move through the deck. Manage your health, upgrade your hero, and play cards as efficiently as possible to win the day.